Doves Diplomats and Diabetes

Author: Milind Watve
Publisher: Springer Science & Business Media
ISBN: 1461444098
Format: PDF, ePub
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Darwinian medicine looks at the ecological and evolutionary roots of disease. A disease is an interaction between a genome and its biotic or abiotic environment and therefore a disease is essentially an ecological process. Good understanding of ecology and a Darwinian way of thinking can give us novel and useful perspectives on health and disease. If we understand the disease process better, we can certainly prevent, control as well as treat diseases in a better way. Although the thought that the origins of obesity and type 2 diabetes (T2D) might lie in our hunter gatherer adaptations is not new, research over the last decade makes us rethink many of the classical concepts. Brain and behavior is increasingly being recognized as central to all the endocrine, metabolic and immunological changes that earmark type 2 diabetes and other metabolic syndrome disorders. A major change in paradigm appears to be on the horizon and the proposed book intends to speed up the paradigm shift by raising important questions, pointing out flaws and inadequacies in the prevalent paradigm and stimulating radical rethinking which would redirect and refine the line of research as well as bring some fundamental changes in drug discovery and clinical practice. ​

Disease Modelling and Public Health

Author:
Publisher: Elsevier
ISBN: 0444639691
Format: PDF, Docs
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Disease Modelling and Public Health, Part A, Volume 36 addresses new challenges in existing and emerging diseases with a variety of comprehensive chapters that cover Infectious Disease Modeling, Bayesian Disease Mapping for Public Health, Real time estimation of the case fatality ratio and risk factor of death, Alternative Sampling Designs for Time-To-Event Data with Applications to Biomarker Discovery in Alzheimer's Disease, Dynamic risk prediction for cardiovascular disease: An illustration using the ARIC Study, Theoretical advances in type 2 diabetes, Finite Mixture Models in Biostatistics, and Models of Individual and Collective Behavior for Public Health Epidemiology. As a two part volume, the series covers an extensive range of techniques in the field. It present a vital resource for statisticians who need to access a number of different methods for assessing epidemic spread in population, or in formulating public health policy. Presents a comprehensive, two-part volume written by leading subject experts Provides a unique breadth and depth of content coverage Addresses the most cutting-edge developments in the field Includes chapters on Ebola and the Zika virus; topics which have grown in prominence and scholarly output

8 in the Box

Author: Raffi Yessayan
Publisher: Random House Digital, Inc.
ISBN: 0345502620
Format: PDF, Kindle
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As Boston is terrorized by a serial killer who leaves behind bathtubs filled with blood, Detective Angel Alves and Assistant D.A. Conrad Darget discover that the only connection among the victims is time spent on juries at the South Bay District Courthouse.

Adipose Tissue Biology

Author: Michael E. Symonds
Publisher: Springer
ISBN: 3319520318
Format: PDF, ePub, Mobi
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The past decade has seen an exponential increase in our knowledge and understanding of adipose tissue biology. This has coincided with the continued rise in obesity across all generations. Clearly despite substantial advances in research into adipose tissue this still has had limited impact on the on-going obesity epidemic across a majority of countries in the world. This book brings together many leading experts in the field to provide an up to date and comprehensive review of the key aspects of adipose tissue. It therefore includes chapters on evolution, development and inflammation together with a detailed review of brown and beige adipose tissue biology and their potential significance in preventing or combating obesity. These chapters are complemented by those on genetics and gender influences, together with nutrition through the life cycle. Ultimately the book provides an overview of the complexities of adipose tissue biology and the continuing challenge to combat obesity in the 21st century.

The Metabolic Ghetto

Author: Jonathan C. K. Wells
Publisher: Cambridge University Press
ISBN: 1316679365
Format: PDF
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Chronic diseases have rapidly become the leading global cause of morbidity and mortality, yet there is poor understanding of this transition, or why particular social and ethnic groups are especially susceptible. In this book, Wells adopts a multidisciplinary approach to human nutrition, emphasising how power relations shape the physiological pathways to obesity, diabetes, hypertension and cardiovascular disease. Part I reviews the physiological basis of chronic diseases, presenting a 'capacity-load' model that integrates the nutritional contributions of developmental experience and adult lifestyle. Part II presents an evolutionary perspective on the sensitivity of human metabolism to ecological stresses, highlighting how social hierarchy impacts metabolism on an intergenerational timescale. Part III reviews how nutrition has changed over time, as societies evolved and coalesced towards a single global economic system. Part IV integrates these physiological, evolutionary and politico-economic perspectives in a unifying framework, to deepen our understanding of the societal basis of metabolic ill-health.

Nehru s India

Author: Nayantara Sahgal
Publisher:
ISBN: 9789385288593
Format: PDF, Kindle
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For much of the country's post-Independence history, Indian politics was dominated by a single towering figure: Jawaharlal Nehru. A leading figure of the Independence movement, and Mahatma Gandhi's chosen successor, Nehru, as India's first prime minister, from 1947 until his death in 1964, was the architect of its birth as a modern nation-state: a sovereign, socialist, secular and democratic republic. In this volume, some of our foremost thinkers and writers examine the different aspects of Nehru's personality and his legacy. Nehru's influence stretched beyond the Freedom Movement and the political and bureaucratic boundaries of prime ministerhood. A man of letters, it was Nehru who initiated the setting up of the Sahitya Akademi devoted to literature, the National School of Drama and the National Institute of Design; just as, in the field of technology and business management, he established the Indian Institutes of Technology and the Indian Institutes of Management across the country. He was equally the force behind the setting up of dams and factories, which he regarded as the temples of modern India Today, in the year of his 125th birth anniversary, the four key dimensions of Indian nationhood, as conceived and implemented by Nehru - democracy, secularism, socialism and non-alignment - have altered to a point where they have changed almost beyond recognition or even abandoned altogether. To quote Mani Shankar Aiyar, '... What needs examination is whether fifty years after he [Nehru] passed away, these are still the defining parameters of India's contemporary nationhood and, if so, how should they be interpreted in the light of present circumstances?' As the debate continues between Nehru's supporters who believe in his enduring contribution, and his detractors who attempt to deny it, the definitive word, perhaps, comes from Nayantara Sahgal, who says in her Introduction, 'No Nehru, no modern India. The ground we stand on was laid in Nehru's time.'

The God Part of the Brain

Author: Matthew Alper
Publisher: Sourcebooks, Inc.
ISBN: 1402236379
Format: PDF, ePub, Mobi
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Is Man the product of a God...or is "God" the product of human evolution? From the dawn of our species, every human culture-no matter how isolated-has believed in some form of a spiritual realm. According to author Matthew Alper, this is no mere coincidence but rather due to the fact that humans, as a species, are genetically predisposed to believe in the universal concepts of a god, a soul and an afterlife. This instinct to believe is the result of an evolutionary adaptation-a coping mechanism-that emerged in our species to help us survive our unique and otherwise debilitating awareness of death. Spiritual seekers and atheists alike will be compelled and transformed by Matthew Alper's classic study of science and religion. The 'God' Part of the Brain has gained critical acclaim from some of the world's leading scientists, secular humanists, and theologians, and is as a must read for anyone who has pondered the question of God's existence, as well as the meaning of our own. Praise for The "God" Part of the Brain "This cult classic in many ways parallels Rene Descartes' search for reliable and certain knowledge...Drawing on such disciplines as philosophy, psychology, and biology, Alper argues that belief in a spiritual realm is an evolutionary coping method that developed to help humankind deal with the fear of death...Highly recommended."— Library Journal "I very much enjoyed the account of your spiritual journey and believe it would make excellent reading for every college student - the resultant residence-hall debates would be the best part of their education. It often occurs to me that if, against all odds, there is a judgmental God and heaven, it will come to pass that when the pearly gates open, those who had the valor to think for themselves will be escorted to the head of the line, garlanded, and given their own personal audience." — Edward O. Wilson, two-time Pulitzer Prize-Winner "This is an essential book for those in search of a scientific understanding of man's spiritual nature. Matthew Alper navigates the reader through a labyrinth of intriguing questions and then offers undoubtedly clear answers that lead to a better understanding of our objective reality." — Elena Rusyn, MD, PhD; Gray Laboratory; Harvard Medical School "What a wonderful book you have written. It was not only brilliant and provocative but also revolutionary in its approach to spirituality as an inherited trait."— Arnold Sadwin, MD, former chief of Neuropsychiatry at the University of Pennsylvania "A lively manifesto...For the discipline's specific application to the matter at hand, I've seen nothing that matches the fury of The 'God' Part of the Brain, which perhaps explains why it's earned something of a cult following." — Salon.com "All 6 billion plus inhabitants of Earth should be in possession of this book. Alper's tome should be placed in the sacred writings' section of libraries, bookstores, and dwellings throughout the world. Matthew Alper is the new Galileo...Immensely important...Defines in a clear and concise manner what each of us already knew but were afraid to admit and exclaim."— John Scoggins, PhD "Vibrant ... vivacious. An entertaining and provocative introduction to speculations concerning the neural basis of spirituality."— Free Inquiry Magazine

A Short History of Nearly Everything

Author: Bill Bryson
Publisher: Anchor Canada
ISBN: 0385674503
Format: PDF, Kindle
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One of the world’s most beloved and bestselling writers takes his ultimate journey -- into the most intriguing and intractable questions that science seeks to answer. In A Walk in the Woods, Bill Bryson trekked the Appalachian Trail -- well, most of it. In In A Sunburned Country, he confronted some of the most lethal wildlife Australia has to offer. Now, in his biggest book, he confronts his greatest challenge: to understand -- and, if possible, answer -- the oldest, biggest questions we have posed about the universe and ourselves. Taking as territory everything from the Big Bang to the rise of civilization, Bryson seeks to understand how we got from there being nothing at all to there being us. To that end, he has attached himself to a host of the world’s most advanced (and often obsessed) archaeologists, anthropologists, and mathematicians, travelling to their offices, laboratories, and field camps. He has read (or tried to read) their books, pestered them with questions, apprenticed himself to their powerful minds. A Short History of Nearly Everything is the record of this quest, and it is a sometimes profound, sometimes funny, and always supremely clear and entertaining adventure in the realms of human knowledge, as only Bill Bryson can render it. Science has never been more involving or entertaining. From the Hardcover edition.

The Impact of Climate Change on Our Life

Author: Abdelnaser Omran
Publisher: Springer
ISBN: 9811077487
Format: PDF, ePub, Docs
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This book introduces the highly topical issue from many different angles, sensitizing readers to the various challenges to human life posed by climate change, identifying possible intentional and inadvertent anthropogenic factors and consequences, and seeking socially and environmentally viable solutions. The book begins by examining the impact of the climate change discussion on science, politics, economy and culture – from its historical origin in the first Club of Rome Report and its inclusion in the UN's SDGs to the Paris Agreement and beyond. Comprising 12 chapters, it analyses the factors which caused the catastrophic 2014 Kelantan flood in Malaysia, focusing on the Kuala Krai district and discusses mud architecture in Wadi Hadramout, Yemen and mitigating the expected effects of climate change on this unique architecture and cultural heritage. It also examines the economic costs of climate change on health and the increased burden on individual expenditures and national health systems. The role of climate change in the water-energy nexus and efforts to increase efficiency in energy and water end-use to increase Queensland’s agricultural sector’s resilience in Australia is addressed, as is water security and climate change issues in developing countries and the potential of partnership procurement strategies for managing sustainable urban water supply in Nigerian cities. It also includes a chapter offering a new approach to waste management, exploring to what extent waste can complicate our daily actions and influence environmental decay, and recommending that renewable materials be sorted and separated from other types of materials to avoid cross-contamination, to increase the value of the materials, and to ease the process of manufacturing. Subsequent chapters identify factors sustaining the municipal solid waste management and practices in Ajdabiya city in Libya, and look at accounting disclosure remedies by exploring areas in which sustainability reporting could expand beyond corporate environmental reporting to additional disclosures, curbing recklessness in pursuing merely economic goals. The book shows – from the perspective of agriculture – how human activities can increase the negative impacts of climate change on lifestyle in Malaysia, suggesting alternative lifestyles and encouraging international cooperative efforts. The last chapters evaluate the impacts of various environmental factors on the local tourism sector in Pakistan, and discuss strategies to tackle climate change, focusing on the opportunities and risks of climate engineering. Since these risks encompass inadvertent negative effects and targeted abuse for covert weather warfare and terrorism that violate the UN’s ENMOD convention, the author recommends viable alternatives to deal with climate change.